منابع مشابه
Metabolism of Polycyclic Compounds. the Metabolism of 1,4-epoxy-1,4-dihydronaphthalene in Rats.
1. 1,4-Epoxy-1,4-dihydronaphthalene is converted by rats into 1,4:2,3-diepoxy-1,2,3,4-tetrahydronaphthalene, which was isolated from the urine. The synthesis of the diepoxide is described. 2. The monoepoxide also yielded a compound that is believed to be 1,4-dihydro-1,4-dihydroxynaphthalene, but no corresponding mercapturic acid was detected. A number of unidentified metabolites of the monoepox...
متن کاملMetabolism of polycyclic compounds. 20. The metabolism of phenanthrene in rabbits and rats: mercapturic acids and related compounds.
Investigations on rats dosed with phenanthrene (Elson, Goulden & Warren, 1945; Crabtree, 1946) showed that there was an increase in the neutralsulphur output in tihe urines, and Gutmann & Wood (1950) found an increase in the radioactivity in the urines when animals were fed with phenanthrene and L-[35S]cysteine. Stekol (1935, 1939) had noticed that the growth of dogs and rats was retarded when ...
متن کاملMetabolism of polycyclic compounds. 22. The metabolism of trans-9,10-dihydro-9,10-dihydroxyphenanthrene in rats.
Dihydrodihydroxy compounds are important intermediates in the metabolic pathways of aromatic hydrocarbons, giving rise to many of the metabolites observed in the urine when the parent hydrocarbons are given to animals. Thus, for example, when tran8-1,2-dihydro-1,2-dihydroxynaphthalene is given to rats it is excreted partly unchanged in conjugation with glucuronic acid, partly as 1-naphthol in c...
متن کاملChemistry of Strained Polycyclic Compounds —vi1,2
The base induced homoketonization of bridgehead cubane alcohol 10, homocubane alcohol 1 and acetate 7, and 1,3-bishomocubane alcohols 13 and 17 has been studied. Under protic conditions, homocubane alcohol 1 and acetate 7 are converted quantitatively into half cage ketones 3 and 8, respectively. by exclusive cleavage of the C4— C7 bond. Similarly, homoketonization of 1,3-bishomocubane alcohols ...
متن کاملOverview of Polycyclic Aromatic Compounds (PAC)
The chemical group of polycyclic aromatic compounds (PAC), including the better-known subgroup of polycyclic aromatic hydrocarbons (PAH) and the heterocyclic aromatic compounds (NSO-PAC, heterocycles), comprise several thousand individual compounds. It is hard to find a comprehensive overview in the literature of these PACs that includes a substantial amount of relevant properties. Here an atte...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1936
ISSN: 0306-3283
DOI: 10.1042/bj0300728